Activatable Chemiluminescent Molecular Probes for Bioimaging and Biosensing

Chemiluminescence (CL) is a very promising method for applications in analytic chemistry and biological systems due to the elimination of external light source, which could reduce autofluorescence interference improve signal-to-noise ratio (SNR) tissue penetration depth. The fluorescent dyes, chemiluminescent initiator, reaction temperature are three crucial factors that determine chemiluminescence efficiency. Up now, significant development probes has been reported high-performance imaging sensing, including based on luminol, imidazopyrazinone, peroxyoxalate, Schaap's dioxetane. In this review, we give an overview current their bioimaging biosensing applications. We also provide perspectives designing with good efficiency longer emission wavelengths.